![]() ![]() The first symptoms may be either neurological or endocrine. Treatment consists of substitutiontherapy, often combined with an increased intake of sodium chloride.Ī syndrome known to occur only in boys consists of a combination of Addison's disease and leucodystrophy, termed adrenoleucodystrophy ( see page 304). ![]() An exact diagnosis usually requires extensive endocrine investigation. Attacks of hypoglycaemia, possibly with convulsions ( see pages 100–101), may, although rarely, occur in Addison's disease. This possibility must be kept in mind when a patient has muscular weakness and hyperpotassaemia. During an acute exacerbation of the disease, and particularly if the patient is given potassium-rich food or medication, the weakness may increase to a severe, occasionally life-threatening, paralysis. One feature that often contributes to the fatigue is a moderate muscular weakness connected with mild atrophy. Hypoactivity of the adrenal cortex, Addison's disease, causes severe fatigue, loss of weight, increased pigmentation, low blood pressure, and electrolyte disturbances. ![]() Ingrid Gamstorp MD, in Paediatric Neurology (Second Edition), 1985 Addison's disease ![]()
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